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Galimedix Therapeutics Completes Phase 1 Study with GAL-101

Galimedix Therapeutics has announced the successful completion of the single ascending dose part of their Phase 1 study of GAL-101. This small molecule, an amyloid beta aggregation modulator, was well tolerated with a favorable safety profile. The study involved 40 healthy volunteers and confirmed GAL-101's suitability for oral administration.

The trial is progressing to the multiple ascending dose phase, expected to conclude in late 2025. Key indications include dry age-related macular degeneration (AMD), glaucoma, and Alzheimer’s disease. The company's Chief Scientific Officer, Hermann Russ, MD, PhD, noted the milestone as vital to GAL-101's development as a potential oral therapy for amyloid beta-related diseases.

Alongside the oral study, a Phase 2 trial of GAL-101 in eyedrop form for dry AMD continues to advance.

R. P.

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