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The Vanguard Group Discloses Stake in Mural Oncology

The Vanguard Group, Inc. has filed a Form 8.3 with the Irish Takeover Panel regarding its interest in Mural Oncology plc, as of September 9, 2025. Under the requirements of the Irish Takeover Panel Act, Vanguard disclosed holding 771,283 ordinary shares, equating to a 4.47% stake in the company. No options or derivatives are reported in this disclosure.

No purchases or sales in cash-settled and stock-settled derivatives have been performed. A small sale of 48 ordinary shares occurred at $2.08 USD per unit. The filing indicates no indemnity or other arrangements regarding the relevant securities and no external agreements concerning options or derivatives.

This disclosure comes under Rule 8.3, acknowledging Vanguard's significant interest, which exceeds the 1% threshold, thereby triggering mandatory reporting. No additional parties are disclosed in connection with this stake.

R. E.

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