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The Vanguard Group, Inc.: Disclosure on Mural Oncology plc

The Vanguard Group, Inc. has released a Form 8.3 concerning its interest in Mural Oncology plc regarding the Irish Takeover Panel Act. The disclosure notes that Vanguard holds 771,731 ordinary shares, equating to 4.47% of Mural Oncology's total shares. This form is essential for adherence to Rule 8.3, addressing shares amounting to 1% or more.

The disclosure was made as of August 19, 2025. Vanguard's dealings included the sale of 16 ordinary shares at $1.80 each. There have been no significant agreements or arrangements influencing the securities beyond this disclosure, with documentation affirming the absence of any Supplemental Form 8 attached.

This filing ensures transparency and compliance with the relevant takeover rules, maintaining market integrity in corporate dealings.

R. P.

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