The Vanguard Group's Disclosure on Mural Oncology Stake

The Vanguard Group, Inc. has issued a Form 8.3 disclosure concerning its interest in Mural Oncology plc. The document is part of compliance under Rule 8.3 of the Irish Takeover Panel Act, 1997. This form pertains to entities holding more than 1% of the relevant securities.

As of July 22, 2025, Vanguard held a 4.47% stake in Mural Oncology, totaling 772,531 $0.01 ordinary shares. The disclosure did not indicate any cash-settled or stock-settled derivatives positions related to these securities.

Additionally, Vanguard reported the sale of 32 ordinary shares at a price of $2.45 per share. No indemnity or option arrangements or agreements concerning the regulatory matters or future acquisitions were reported.

In conclusion, Vanguard's holding reflects a significant position in Mural Oncology but without additional derivative stakes or external agreements.