UCB (EBR:UCB) UCB Media Room: Praxis Precision Medicines Epilepsy Research Collaboration
Directive transparence : information réglementée
13/12/2022 22:05
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** UCB and Praxis Precision Medicines Announce Epilepsy Research Collaborat=
ion
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BRUSSELS (Belgium) and BOSTON, Massachusetts (USA), December 13th, 2022 (22=
:01 CET) =E2=80=94 UCB, a global biopharmaceutical company (EURONEXT BRUSSE=
LS: UCB), and Praxis Precision Medicines, Inc. (NASDAQ: PRAX), a clinical-s=
tage biopharmaceutical company, today announced a strategic collaboration, =
based upon Praxis=E2=80=99 PRAX-020 program, for the discovery of small mol=
ecule therapeutics as potential treatments of KCNT1 related epilepsies.
=E2=80=9CWe are excited to partner with UCB, a global leader in epilepsy dr=
ug development, as we work together toward a novel approach for the treatme=
nt of KCNT1 related epilepsy, which has no approved therapies currently,=E2=
=80=9D said Marcio Souza, president and chief executive officer of Praxis. =
=E2=80=9COur internal research efforts give us confidence that small molecu=
les can selectively inhibit the KCNT1 channel, and potentially could be an =
effective treatment for individuals suffering from KCNT1 related epilepsy. =
The collaboration with UCB validates this approach and will allow us to acc=
elerate efforts toward a potential treatment for KCNT1 patients.=E2=80=9D
Under the terms of the collaboration, UCB retains an exclusive option to in=
-license global development and commercialization rights to any resulting K=
CNT1 small molecule development candidate. Praxis will receive an upfront p=
ayment from UCB, and if the option is exercised by UCB, would be eligible t=
o receive an option fee and future success-based development and commercial=
ization milestone payments, for a total of up to approximately $100 million=
, in addition to tiered royalties on net sales of any resulting products fr=
om the collaboration. Further financial details of the agreement were not d=
isclosed.
=E2=80=9CUCB is dedicated to the discovery and development of treatments fo=
r epilepsy, including rare and genetic epilepsies, with an ambition to deve=
lop solutions that move from symptomatic relief to those that could address=
the root causes of disease,=E2=80=9D said Dhaval Patel, chief scientific o=
fficer of UCB. =E2=80=9CPraxis=E2=80=99 genetics-driven approach has led to=
compelling preclinical proof of concept, and we look forward to progressin=
g this novel research program together for the benefit of individuals and f=
amilies affected by this devastating form of epilepsy.=E2=80=9D
About UCB
UCB, Brussels, Belgium (www.ucb.com) is a global biopharmaceutical company =
focused on the discovery and development of innovative medicines and soluti=
ons to transform the lives of people living with severe diseases of the imm=
une system or of the central nervous system. With more than 8,600 people in=
approximately 40 countries, UCB generated revenue of =E2=82=AC5.8 billion =
in 2021. UCB is listed on Euronext Brussels (symbol: UCB). Follow us on Twi=
tter: @UCB_news
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or commercially successful as UCB may have believed at the start of such p=
artnership. UCB=E2=80=99s efforts to acquire other products or companies an=
d to integrate the operations of such acquired companies may not be as succ=
essful as UCB may have believed at the moment of acquisition. Also, UCB or =
others could discover safety, side effects or manufacturing problems with i=
ts products and/or devices after they are marketed. The discovery of signif=
icant problems with a product similar to one of UCB=E2=80=99s products that=
implicate an entire class of products may have a material adverse effect o=
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stems.=C2=A0
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UCB is providing this information, including forward-looking statements, on=
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UCB is following the worldwide developments diligently to assess the financ=
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to update any information contained in this press release, either to confir=
m the actual results or to report or reflect any change in its forward-look=
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ircumstances on which any such statement is based, unless such statement is=
required pursuant to applicable laws and regulations.=C2=A0
Additionally, information contained in this document shall not constitute a=
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For further information
R&D Communications - UCB
Scott Fleming
Scott.fleming@ucb.com / +44 7702777378
Investor Relations - UCB
Antje Witte
antje.witte@ucb.com / +32.2.559.94.14
Investor Contact - Praxis
Alex Kane=C2=A0
Praxis Precision Medicines
investors@praxismedicines.com / 617-300-8481
Media Contact - Praxis
Ian Stone
Canale Communications
Ian.stone@canalecomm.com / 619-849-5388
=C2=A0
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